Easy Homemade Chicken Pot Pie Casserole Recipe

Name: Easy Homemade Chicken Pot Pie Casserole Recipe
Prep time: 15 min
Cook time: 45 min
Total time: 1 h
Yield: 6 servings
Ingredients: 2 cups cooked chicken, shredded; 1 cup frozen mixed vegetables; 1 can cream of chicken soup; 1/2 cup milk; 1 teaspoon onion powder; 1 teaspoon garlic powder; 1 can refrigerated biscuit dough; Salt and pepper to taste

Highlighted under: Comfort Food

Create a comforting and delicious dinner with this Easy Homemade Chicken Pot Pie Casserole. This family-friendly dish features tender chicken, fresh vegetables, and a creamy sauce all topped with flaky biscuit crust. Perfect for busy weeknights, this casserole is sure to become a favorite at your table.

Created by

Lillian Hayes

Last updated on 2025-12-12T10:01:20.992Z

This Chicken Pot Pie Casserole is a delightful twist on the classic recipe. The combination of juicy chicken, mixed vegetables, and a creamy sauce encased in a crispy biscuit topping makes it a comforting dish that the whole family will adore.

A Classic Comfort Food

There's something inherently comforting about a chicken pot pie, and this casserole version takes that warm, nostalgic feeling to a new level. It combines the tender flavors of succulent chicken and savory vegetables, all enveloped in a rich, creamy sauce. This dish hits all the right notes for a cozy family dinner, encouraging everyone to gather around the table and enjoy a fulfilling meal together. With each bite, you’ll be reminded of home-cooked dinners and the love that goes into them.

The beauty of a casserole is its adaptability; you can easily customize this recipe to suit your family's preferences. Whether it's swapping out the mixed vegetables for your favorites or adding in some herbs and spices for an extra kick, the possibilities are endless. This makes it a wonderful dish for anyone looking to add their personal touch to a classic recipe, making every family dinner unique.

Easy Preparation for Busy Nights

In today's fast-paced world, finding the time to create a fulfilling home-cooked meal can be a challenge. Fortunately, this Easy Homemade Chicken Pot Pie Casserole fits perfectly into your busy schedule. With only a few basic steps, you'll have a hearty meal prepared and ready to bake in no time. It’s an ideal recipe for weeknight dinners when you're short on time but still want something homemade and satisfying.

The preparation steps are straightforward, making it easy for even novice cooks to follow along. You can also save time by using pre-cooked chicken and frozen vegetables, ensuring your dinner comes together quickly without sacrificing flavor or satisfaction. It’s a great way to streamline your cooking process while still providing a comforting meal your family will love.

Perfect for Leftovers and Meal Prep

One of the many advantages of this casserole is its ability to be reheated for leftovers. After enjoying the meal, simply store any remaining casserole in the refrigerator. It will taste just as delicious the next day, making it a fantastic option for meal prep or busy weekdays. Reheating takes only a short time, allowing you to enjoy a home-cooked meal without the extra effort.

Additionally, this casserole can be made ahead of time. Prepare it in advance and store it in the freezer, then bake it when you're ready. This versatility makes it a smart choice for families wanting to simplify dinner or those who enjoy cooking in bulk. With just a little planning, you can always have a comforting meal on hand.

Ingredients

Ingredients for Chicken Pot Pie Casserole

2 cups cooked chicken, shredded
1 cup frozen mixed vegetables
1 can cream of chicken soup
1/2 cup milk
1 teaspoon onion powder
1 teaspoon garlic powder
1 can refrigerated biscuit dough
Salt and pepper to taste

Gather all ingredients before you start cooking.

Instructions

Preheat the Oven

Preheat your oven to 375°F (190°C).

Combine the Filling

In a large bowl, mix together the shredded chicken, frozen vegetables, cream of chicken soup, milk, onion powder, garlic powder, salt, and pepper.

Transfer to Baking Dish

Pour the chicken mixture into a greased 9x13 inch baking dish, spreading it out evenly.

Add Biscuit Topping

Open the biscuit dough and cut each biscuit into quarters. Scatter the biscuit pieces over the top of the chicken mixture.

Bake the Casserole

Bake in the preheated oven for 25-30 minutes, or until the biscuits are golden brown and cooked through.

Let the casserole cool for a few minutes before serving.

Tips for the Best Casserole

To ensure your casserole turns out perfectly, make sure to evenly combine all ingredients before transferring them to the baking dish. This ensures that every bite is packed with flavor and you don’t miss out on any delicious creaminess. If you prefer a bit of extra flavor, consider adding sautéed onions or a dash of your favorite hot sauce to the mixture.

Additionally, keeping an eye on the baking process is crucial. Ovens can vary in temperature, so check your casserole around the 25-minute mark. You want the biscuits to be golden brown and the filling bubbling slightly, which indicates that it is heated through and ready to serve.

Serving Suggestions

When it comes to serving this chicken pot pie casserole, it's great on its own but can be paired with a simple side salad for added freshness. The crisp greens will complement the richness of the casserole beautifully, providing a balanced meal. Consider using a light vinaigrette dressing to enhance the flavors without overwhelming the dish.

For those who enjoy a bit of crunch, a side of garlic bread or buttery biscuits can also elevate the dining experience. These accompaniments not only add texture but also make for a more filling meal, ensuring everyone leaves the table satisfied.

Storage and Reheating

Storing leftovers properly is essential for maintaining the quality of this casserole. Make sure to allow it to cool completely before transferring it to an airtight container. It can be kept in the refrigerator for up to three days, or you can freeze it for longer storage. When freezing, it’s helpful to label the container with the date and an estimate of when it should be consumed for best quality.

When it's time to reheat, you can either microwave individual portions or bake the entire casserole in the oven. If baking from frozen, be sure to cover it with foil for the first part of the cooking time to prevent over-browning of the biscuit topping. This ensures a delightful meal that's just as good as the first time you made it!

Questions About Recipes

→ Can I use leftover turkey instead of chicken?

Yes! Leftover turkey works great in this recipe.

→ How can I make this dish healthier?

You can replace the cream of chicken soup with a low-fat version and use whole grain biscuits.